Email this article Synthesis of new chiral amidophosphite ligands and their application in hydrogenation of benzodiazepinones and enamides
- Authors: Sokolovskaya M.V.1, Lyubimov S.E.1, Davankov V.A.1
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Affiliations:
- A. N. Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences
- Issue: Vol 66, No 7 (2017)
- Pages: 1213-1216
- Section: Full Articles
- URL: https://journal-vniispk.ru/1066-5285/article/view/240926
- DOI: https://doi.org/10.1007/s11172-017-1875-8
- ID: 240926
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Abstract
New chiral amidophosphites were synthesized and tested in the Ir-catalyzed hydrogenation of 4-substituted 1,3-dihydro-2H-1,5-benzodiazepin-2-ones and Rh-catalyzed hydrogenation of dehydro amino acid derivatives. The triphenylphosphine additive can considerably increase the enantioselectivity of both processes.
About the authors
M. V. Sokolovskaya
A. N. Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences
Email: lssp452@mail.ru
Russian Federation, 28 ul. Vavilova, Moscow, 119991
S. E. Lyubimov
A. N. Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences
Author for correspondence.
Email: lssp452@mail.ru
Russian Federation, 28 ul. Vavilova, Moscow, 119991
V. A. Davankov
A. N. Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences
Email: lssp452@mail.ru
Russian Federation, 28 ul. Vavilova, Moscow, 119991
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