Email this article Synthesis and biological activity of arylaliphatic N-(2-aminoethyl)-N-(2-hydroxy-2-phenylethyl)carboxamides
- Authors: Hoang D.Q.1, Borisova E.Y.1, Borisova N.Y.1, Asilova N.Y.1, Kaldyrkaeva O.S.2, Arzamastsev E.V.2, Terekhova O.A.2, Afanas’eva E.Y.2, Levitskaya E.L.2
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Affiliations:
- Moscow Technological University (Institute of Fine Chemical Technology)
- Russian Cardiology Research and Production Complex
- Issue: Vol 67, No 1 (2018)
- Pages: 131-136
- Section: Article
- URL: https://journal-vniispk.ru/1066-5285/article/view/241982
- DOI: https://doi.org/10.1007/s11172-018-2048-0
- ID: 241982
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Abstract
N-(2-Aminoethyl)-N-(2-hydroxy-2-phenylethyl)carboxamides were synthesized from styrene oxide by ring opening with N,N-disubstituted ethylenediamines followed by N-acylation. Synthesized compounds have pronounced antiarrhythmic activity and low toxicity.
About the authors
D. Q. Hoang
Moscow Technological University (Institute of Fine Chemical Technology)
Author for correspondence.
Email: quanghoang1510@gmail.com
Russian Federation, 86 prosp. Vernadskogo, Moscow, 119571
E. Ya. Borisova
Moscow Technological University (Institute of Fine Chemical Technology)
Email: quanghoang1510@gmail.com
Russian Federation, 86 prosp. Vernadskogo, Moscow, 119571
N. Yu. Borisova
Moscow Technological University (Institute of Fine Chemical Technology)
Email: quanghoang1510@gmail.com
Russian Federation, 86 prosp. Vernadskogo, Moscow, 119571
N. Yu. Asilova
Moscow Technological University (Institute of Fine Chemical Technology)
Email: quanghoang1510@gmail.com
Russian Federation, 86 prosp. Vernadskogo, Moscow, 119571
O. S. Kaldyrkaeva
Russian Cardiology Research and Production Complex
Email: quanghoang1510@gmail.com
Russian Federation, 15a ul. 3-ya Cherepkovskaya, Moscow, 121552
E. V. Arzamastsev
Russian Cardiology Research and Production Complex
Email: quanghoang1510@gmail.com
Russian Federation, 15a ul. 3-ya Cherepkovskaya, Moscow, 121552
O. A. Terekhova
Russian Cardiology Research and Production Complex
Email: quanghoang1510@gmail.com
Russian Federation, 15a ul. 3-ya Cherepkovskaya, Moscow, 121552
E. Yu. Afanas’eva
Russian Cardiology Research and Production Complex
Email: quanghoang1510@gmail.com
Russian Federation, 15a ul. 3-ya Cherepkovskaya, Moscow, 121552
E. L. Levitskaya
Russian Cardiology Research and Production Complex
Email: quanghoang1510@gmail.com
Russian Federation, 15a ul. 3-ya Cherepkovskaya, Moscow, 121552
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