Chemospecific synthesis of 2-acetoxyindole-3-carbonitriles catalyzed by Cu(acac)2


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Resumo

A chemospecific one-pot synthesis of easily isolable 2-acetoxyindole-3-carbonitriles was described. The intermediate 2-oxindole-3-carbonitriles successfully prepared from 2-cyano diazoacetanilides without isolation were treated with acetyl chloride and triethylamine to give 2-acetoxyindole-3-carbonitriles. The developed one-pot approach showed broad substrate scope.

Sobre autores

Shanyan Mo

State Key Laboratory of Chemical Engineering Resource, Department of Organic Chemistry, Faculty of Science, Beijing University of Chemical Technology

Email: jxxu@mail.buct.edu.cn
República Popular da China, Beijing, 100029

Jianzhuo Tu

State Key Laboratory of Chemical Engineering Resource, Department of Organic Chemistry, Faculty of Science, Beijing University of Chemical Technology

Email: jxxu@mail.buct.edu.cn
República Popular da China, Beijing, 100029

Jiaxi Xu

State Key Laboratory of Chemical Engineering Resource, Department of Organic Chemistry, Faculty of Science, Beijing University of Chemical Technology

Autor responsável pela correspondência
Email: jxxu@mail.buct.edu.cn
República Popular da China, Beijing, 100029

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