Synthesis of glutaryl-containing derivatives of GRGD and KRGD peptides
- 作者: Demin A.M.1, Vakhrushev A.V.1, Tumashov A.A.1,2, Krasnov V.P.1
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隶属关系:
- I. Ya. Postovsky Institute of Organic Synthesis, Ural Branch of the Russian Academy of Sciences
- Institute of Natural Sciences and Mathematics, Ural Federal University
- 期: 卷 68, 编号 12 (2019)
- 页面: 2316-2324
- 栏目: Full Articles
- URL: https://journal-vniispk.ru/1066-5285/article/view/243565
- DOI: https://doi.org/10.1007/s11172-019-2705-y
- ID: 243565
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详细
New derivatives of tetrapeptides GRGD (Gly-Arg(Pbf)-Gly-Asp(OMe)-OMe) and KRGD (Boc-Lys-Arg(Pbf)-Gly-Asp(OMe)-OMe) containing a glutaric acid fragment as a linker were synthesized. The linker provides the possibility for binding these derivatives to other biologically active molecules or nanoparticles.
作者简介
A. Demin
I. Ya. Postovsky Institute of Organic Synthesis, Ural Branch of the Russian Academy of Sciences
编辑信件的主要联系方式.
Email: demin@ios.uran.ru
俄罗斯联邦, 22 ul. S. Kovalevskoi, Ekaterinburg, 620990
A. Vakhrushev
I. Ya. Postovsky Institute of Organic Synthesis, Ural Branch of the Russian Academy of Sciences
Email: demin@ios.uran.ru
俄罗斯联邦, 22 ul. S. Kovalevskoi, Ekaterinburg, 620990
A. Tumashov
I. Ya. Postovsky Institute of Organic Synthesis, Ural Branch of the Russian Academy of Sciences; Institute of Natural Sciences and Mathematics, Ural Federal University
Email: demin@ios.uran.ru
俄罗斯联邦, 22 ul. S. Kovalevskoi, Ekaterinburg, 620990; 19 ul. Mira, Ekaterinburg, 620002
V. Krasnov
I. Ya. Postovsky Institute of Organic Synthesis, Ural Branch of the Russian Academy of Sciences
Email: demin@ios.uran.ru
俄罗斯联邦, 22 ul. S. Kovalevskoi, Ekaterinburg, 620990
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