The subject of the study is the emotional sphere and cognitive functions (memory, attention, thinking) of patients with HIV infection. The object of the study is the patients themselves. The author provides a detailed analysis of the cognitive impairments in this group of patients, which significantly affect treatment adherence, emotional stability, and overall quality of life. The focus is on the experience of conducting group training, the effectiveness of which is demonstrated by improvements of participants' emotional state and cognitive functions. The study emphasizes the importance of a personalized approach to assessing and correcting cognitive functions and emotional disorders, considering factors such as disease stage, comorbidities, psychoemotional state, and individual patient characteristics. Based on these findings, the author developed a training program tailored to meet the needs of this group. In the work we used an information questionnaire, Schulte tables, “10 words memorization test”, “Munsterberg test”, methods “Essential attributes”, “Exclusion of superfluous” (non-verbal version), method “Complex analogies”, “Psychopathological symptomatology severity questionnaire”, method of diagnostics of irrational attitudes A. Ellis and method “Life satisfaction index”. Psychodiagnostic examination was conducted before the training and after every eight sessions. The main conclusions of the study are the proven effectiveness of the training in improving memory (of 39% of participants), attention (of 83%), logical thinking (of 36%) and emotional state, including a significant reduction in somatization, obsessive-compulsive manifestations, depression and anxiety (of 47-63%). Questionnaire survey of participants showed high satisfaction with the training and improvement of cognitive functions and emotional state, which confirms the relevance of the approach. Correlation analysis showed a significant relationship between emotional tension and irrational attitudes, which is important to consider in rehabilitation programs. The training program was adapted to the peculiarities of the participants, which allowed to achieve improvements in cognitive and emotional spheres.