Email this article Analysis of Causes of Sudden Death Among Russian Railway Workers
- Authors: Zhidkova E.A.1,2, Gutor E.M.1, Gurevich K.G.2,3, Makogon N.V.4, Shugushev Z.K.5, Orlov D.O.6, Dzhioyeva O.N.2,4, Drapkina O.M.2,4
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Affiliations:
- Central Directorate of Healthcare — Branch of Joint Stock Company ‘Russian Railways’
- A. I. Yevdokimov Moscow State University of Medicine and Dentistry
- Research Institute of Healthcare Organization and Medical Management of Moscow Healthcare Department
- National Medical Research Center for Therapy and Preventive Medicine
- RZD-Medicine
- City Clinical Hospital No. 24 of Moscow Healthcare Department
- Issue: Vol 30, No 4 (2022)
- Pages: 497-506
- Section: Original study
- URL: https://journal-vniispk.ru/pavlovj/article/view/252588
- DOI: https://doi.org/10.17816/PAVLOVJ110985
- ID: 252588
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Abstract
INTRODUCTION: Health protection of railway workers of various professional groups increases the safety of railway transport, the prestige of the profession and reduces morbidity and mortality from the most common causes in this group of patients.
AIM: To analyze the risk factors of sudden death among Russian Railways workers.
MATERIALS AND METHODS: The design of the study is made according to the ‘case-control’ type. Analysis was carried out of all cases of sudden death (SD) of employees of JSCo ‘Russian Railways’ (RR) in the period from 2009 to 2021 (n = 412). The comparison group consisted of 411 employees of RR who were undergoing periodical medical examination. The groups were formed on the basis of age, employment period, gender, profession. To assess the diagnostic significance of the quantitative signs in predicting a certain outcome, the method of analysis of ROC curves was used.
RESULTS: The chances of death for workers of RR increased in case of past myocardial infarction, and also depended on the type of intervention (p < 0.001). The threshold value of the BMI index in the cut-off point, which corresponded to the highest value of Youden index, was 27.1 kg/m2. In the group of sudden deaths, there were 1.8 times more smokers and 2 times less individuals with total cholesterol level exceeding 5 mmol/l than in the comparison group (p < 0.001). A prognostic model was developed by ROC-analysis to determine the probability of mortality. The sensitivity and specificity of the model were 79.5% and 91.9%, respectively.
CONCLUSION: A prognostic model was developed to determine the probability of sudden death in Russian railway workers, with the sensitivity and specificity 79.5% and 91.9%, respectively. However, the present study did not permit to reveal predictors of sudden death specific of the workers of RR.
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##article.viewOnOriginalSite##About the authors
Elena A. Zhidkova
Central Directorate of Healthcare — Branch of Joint Stock Company ‘Russian Railways’; A. I. Yevdokimov Moscow State University of Medicine and Dentistry
Email: genmedc@gmail.com
ORCID iD: 0000-0002-6831-9486
SPIN-code: 5915-7535
Cand. Sci. (Med.)
Russian Federation, Moscow; MoscowEkaterina M. Gutor
Central Directorate of Healthcare — Branch of Joint Stock Company ‘Russian Railways’
Email: gutorem23@mail.ru
ORCID iD: 0000-0001-5725-5918
Russian Federation, Moscow
Konstantin G. Gurevich
A. I. Yevdokimov Moscow State University of Medicine and Dentistry; Research Institute of Healthcare Organization and Medical Management of Moscow Healthcare Department
Email: kgurevich@mail.ru
ORCID iD: 0000-0002-7603-6064
SPIN-code: 4344-3045
MD, Dr. Sci. (Med.), Professor
Russian Federation, Moscow; MoscowNikita V. Makogon
National Medical Research Center for Therapy and Preventive Medicine
Email: nikimakogon@gmail.ru
ORCID iD: 0000-0003-3288-7315
Russian Federation, Moscow
Zaur Kh. Shugushev
RZD-Medicine
Email: Zaur937@mail.ru
ORCID iD: 0000-0002-5335-5062
SPIN-code: 3390-4559
MD, Dr. Sci. (Med.), Professor
Russian Federation, MoscowDenis O. Orlov
City Clinical Hospital No. 24 of Moscow Healthcare Department
Email: rizhiy17@mail.ru
ORCID iD: 0000-0002-0994-8880
Russian Federation, Moscow
Ol’ga N. Dzhioyeva
A. I. Yevdokimov Moscow State University of Medicine and Dentistry; National Medical Research Center for Therapy and Preventive Medicine
Email: dzhioevaon@gmail.com
ORCID iD: 0000-0002-5384-3795
SPIN-code: 1803-5454
MD, Dr. Sci. (Med.), Professor
Russian Federation, Moscow; MoscowOksana M. Drapkina
A. I. Yevdokimov Moscow State University of Medicine and Dentistry; National Medical Research Center for Therapy and Preventive Medicine
Author for correspondence.
Email: drapkina@bk.ru
ORCID iD: 0000-0002-4453-8430
SPIN-code: 4456-1297
MD, Dr. Sci. (Med.), Professor
Russian Federation, Moscow; MoscowReferences
- Gutor EM, Zhidkova EA, Gurevich KG. Risk factors for developing diseases in locomotive crew workers. Russian Journal of Occupational Health and Industrial Ecology. 2022;61(1):43–52. (In Russ). doi: 10.31089/1026-9428-2022-62-1-43-52
- Zhidkova EA, Gurevich KG, Kontsevaya AV, et al. Specifics of corporate health programs for railway workers. Cardiovascular Therapy and Prevention. 2021;20(4):2900. (In Russ). doi: 10.15829/1728-8800-2021-2900
- Wikland B. Medically unattended fatal cases of ischaemic heart disease in a defined population. Acta Medica Scandinavica. Supplementum. 1971;524:3–78.
- Kudrin VA, Kraevoj SA. Preventive medical questions of premature death rate on the railway transport. Actual Problems of Transport Medicine. 2008;(1):110–3. (In Russ).
- Kazidaeva EN, Sergunina I.N., Venevtseva Yu.L. Dynamics of cardiovascular risk factors in railway crews. Cardiovascular Therapy and Prevention. 2018;17(3):53–8. (In Russ). doi: 10.15829/1728-8800-2018-3-53-58
- Shavrukov YuM. Development of urban rail transport. Science & Education. Bauman Moscow State Technical University. 2014;(8):25–47. Available at: http://engineering-science.ru/doc/727439.html. Accessed: 2022 September 20. (In Russ).
- Vybranets AV. Bor’ba s avtomobilizatsiy s pomoshch’yu polozhitel’nykh kharakteristik legkogo rel’sovogo transporta. Studencheskiy Vestnik. 2020;(22, Pt 7):82–4. Available at: https://www.internauka.org/journal/stud/herald/120. Accessed: 2022 September 20. (In Russ).
- Shamloo AS, Dilk P, Dagres N. Prevention of sudden cardiac death. Herz. 2022;47(2):135–40. doi: 10.1007/s00059-022-05106-w
- Farioli A, Christophi CA, Quarta CC, et al. Incidence of sudden cardiac death in a young active population. Journal of the American Heart Association. 2015;4(6):e001818. doi: 10.1161/JAHA.115.001818
- Maksimov IB, Fesenko MA, Sinopalnikov VI, et al. Telemetric control in assessing the working capacity of transport industry employees. Russian Journal of Occupational Health and Industrial Ecology. 2021;61(3):191–6. (In Russ). doi: 10.31089/1026-9428-2021-61-3-191-196
- Paratz ED, van Heusden A, Zentner D, et al. Prevalence of Coronary Artery Anomalies in Young and Middle-Aged Sudden Cardiac Death Victims (from a Prospective State-Wide Registry). The American Journal of Cardiology. 2022;175:127–30. doi: 10.1016/j.amjcard.2022.03.055
- Vähätalo J, Holmström L, Pakanen L, et al. Coronary Artery Disease as the Cause of Sudden Cardiac Death Among Victims < 50 Years of Age. The American Journal of Cardiology. 2021;147:33–8. doi: 10.1016/j.amjcard.2021.02.012
- Hanada K, Sasaki S, Seno M, et al. Reduced Left Ventricular Ejection Fraction Is a Risk for Sudden Cardiac Death in the Early Period After Hospital Discharge in Patients With Acute Myocardial Infarction. Circulation Journal. 2022;86(10):1490–8. doi: 10.1253/circj.cj-21-0999
- Aune D, Schlesinger S, Norat T, et al. Tobacco smoking and the risk of sudden cardiac death: a systematic review and meta-analysis of prospective studies. European Journal of Epidemiology. 2018;33(6):509–21. doi: 10.1007/s10654-017-0351-y
- Cheng Y–J, Chen Z–G, Yao F–J, et al. Airflow obstruction, impaired lung function and risk of sudden cardiac death: a prospective cohort study. Thorax. 2022;77(7):652–62. doi: 10.1136/thoraxjnl-2020-215632
- Kunutsor SK, Zaccardi F, Karppi J, et al. Is High Serum LDL/HDL Cholesterol Ratio an Emerging Risk Factor for Sudden Cardiac Death? Findings from the KIHD Study. Journal of Atherosclerosis and Thrombosis. 2017;24(6):600–8. doi: 10.5551/jat.37184
- Remme CA. Sudden Cardiac Death in Diabetes and Obesity: Mechanisms and Therapeutic Strategies. The Canadian Journal of Cardiology. 2022;38(4):418–26. doi: 10.1016/j.cjca.2022.01.001
- Tirandi A, Carbone F, Montecucco F, et al. The role of metabolic syndrome in sudden cardiac death risk: Recent evidence and future directions. European Journal of Clinical Investigation. 2022;52(2):e13693. doi: 10.1111/eci.13693
- Kochi AN, Vettor G, Dessanai MA, et al. Sudden Cardiac Death in Athletes: From the Basics to the Practical Work-Up. Medicina (Kaunas). 2021;57(2):168. doi: 10.3390/medicina57020168
- Verrier RL, Kumar K, Nearing BD. Basis for sudden cardiac death prediction by T-wave alternans from an integrative physiology perspective. Heart Rhythm. 2009;6(3):416–22. doi: 10.1016/j.hrthm.2008.11.019
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