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发表评论 VERIFICATION AND TREATMENT OF RESISTANT CHRONIC RHINOSINUSITIS WITH NASAL POLYPS AT MULTIMORBID CARDIOVASCULAR PATHOLOGY
- 作者: Aflitonov MA1, Artyushkin SA1, Partsernyak SA1,2, Mironenko AN1,2, Partsernyak AS3, Naumov SY4, Bezrukova EV1, Topanova AA1
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隶属关系:
- Northwestern State Medical university named after I.I. Mechnikov
- City hospital № 15
- Military medical academy named after S.M. Kirov
- City hospital № 40
- 期: 卷 9, 编号 2 (2017)
- 页面: 90-96
- 栏目: Reviews
- URL: https://journal-vniispk.ru/vszgmu/article/view/8565
- DOI: https://doi.org/10.17816/mechnikov20179290-96
- ID: 8565
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Objective: Identify the diagnostic signs for chronic rhinosinusitis with nasal polyps (CRSwNP & resistant forms) with multimorbid cardiovascular pathology (MCVP) (coronary artery disease (CAd), hypertension, metabolic syndrome (MS). Identify effectiveness of photodynamic therapy in CRSwNP treatment. Design and methods: The study included 75 patients (mean age 35,8±7,93, 39,2% - female,60,8% - male) with CRSwNP and MCVP divided into 3 groups by simple random sampling. Patients in group 1 (n = 27) received standard therapy CRSwNP, hypertension, CAd, NPMd, 8-weeks anti- bacterial and leukotriene receptor antagonists treatment. Surgical interventions history of the last 5 five years: from 1 to 2. Patients in group 2 (n = 28) received standard therapy CRSwNP, hypertension, CAd, NPMd, 8-weeks antibacterial and leukotriene receptor antagonists treatment. Surgical inter- ventions history of the last 5 five years: more than 3. Patients of group 3 (n = 20) received standard therapy CRSwNP, hypertension, CAd, NPMd, 8-weeks antibacterial treatment, 8-weeks leukotriene receptor antagonists treatment and sessions of photodynamic therapy of the paranasal sinuses. Surgical interventions history of the last 5 five years: more than 3. used in the study: complex psychological test methods, ENT and laboratory-instrumental evaluation of the cardiovascular system. Results: depres- sion was detected in 46,3%, 71,9%, 58,3% of patients, (first, second, third groups). Types «non-dipper» and «night-peaker» found in patients 2nd and 3rd groups- corresponds with (CRSwNP & resistant forms). Bone transformation zone as a result of chronic inflammation within the ethmoidal labyrinth and maxillary sinuses identified in the second and third patients group (85% of cases). The use of pho- todynamic therapy in the resistant CRSwNP forms treatment improves the functional indicators of the nasal cavity and paranasal sinuses. Conclusions: Patients with CRSwNP have symptoms of depression and «non-dipper» and «night-peaker» patterns. All CRSwNP patients are defined trigger points with areas of chronic osteitis and odontogenic osteomyelitis. The use of photodynamic therapy for CRSwNP treatment, reduces the number of CRSwNP recurrence.
作者简介
M Aflitonov
Northwestern State Medical university named after I.I. Mechnikov
S Artyushkin
Northwestern State Medical university named after I.I. Mechnikov
S Partsernyak
Northwestern State Medical university named after I.I. Mechnikov; City hospital № 15
A Mironenko
Northwestern State Medical university named after I.I. Mechnikov; City hospital № 15
A Partsernyak
Military medical academy named after S.M. Kirov
S Naumov
City hospital № 40
E Bezrukova
Northwestern State Medical university named after I.I. Mechnikov
A Topanova
Northwestern State Medical university named after I.I. Mechnikov
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