Vol 16, No 5-6 (2016)
- Year: 2016
- Articles: 44
- URL: https://journal-vniispk.ru/2410-3764/issue/view/1365
- DOI: https://doi.org/10.17816/2072-2354.2016.0.5-6
Articles
QUALITY OF LIFE IN PATIENTS ON HEMODIALYSIS TREATMENT PROGRAM (LITERATURE REVIEW)
Abstract
This review of literature is devoted to the modern quality of life in patients undergoing hemodialysis treatment program. Direction of research, compilation of assessment of quality of life in hemodialysis patients are indicated in the review. The review concludes that despite numerous studies of foreign and Russian scientists in this area, the problem has not been studied completely.
Aspirantskiy Vestnik Povolzhiya. 2016;16(5-6):7-11
7-11
THE VALUE OF THE EVALUATION OF HUMORAL IMMUNITY IN DUST LUNG DISEASES
Abstract
The article is devoted to improving the quality of early diagnosis of pulmonary dust diseases, through the study of immune mechanisms and cytokine regulation in the development of the proliferative phase of inflammation in the remodeling process in bronchial tubes.
Aspirantskiy Vestnik Povolzhiya. 2016;16(5-6):12-15
12-15
THE PECULIARITIES OF MORTALITY IN COMMUNITY-ACQUIRED PNEUMONIA OF SPECIFIC AND NONSPECIFIC ETIOLOGY IN PATIENTS WITH HIV. LITERATURE REVIEW
Abstract
Community-acquired pneumonia and tuberculosis are common diseases of the lungs which often lead to death in patients with HIV-infection. This problem can be as interdisciplinary. It requires new approaches to both the diagnosis and tactics of patients with comorbid pathology. Causes of death (HIV-infection or pneumonia) are currently controversial and discussed. This article provides a review of published data on the current state of the problem of determining the risk of unfavorable outcome of tuberculosis and nonspecific community-acquired pneumonia in patients with HIV-infection.
Aspirantskiy Vestnik Povolzhiya. 2016;16(5-6):16-21
16-21
MICROBIOLOGICAL MONITORING OF BIOPSY MATERIAL IN PATIENTS WITH ULCERATIVE COLITIS
Abstract
The article presents data on the qualitative composition of microflora isolated from biopsy material of 17 patients with ulcerative colitis. The recorded substantial diversity of microflora require accurate species identification and development of standard procedures for the allocation of micro-organisms from biopsy specimens in patients with ulcerative colitis.
Aspirantskiy Vestnik Povolzhiya. 2016;16(5-6):22-25
22-25
CLINICAL AND LABORATORY CHARACTERISTICS OF PATIENTS WITH HBEAG-NEGATIVE CHRONIC HEPATITIS B WITH DIFFERENT LEVELS OF VIRAL LOAD IN THE SERUM
Abstract
Our study demonstrates the relationship between of viral load with clinical, biochemical and immunological (IL-2, INF-α, INF-γ) tests in patients with HBeAg-negative НBV, n=132 analyzed the relationship. It was found that 75% of patients with HBeAg-negative НBV had viral load more than 20,000 IU\ml (n=99), in other cases, the amount of virus in the blood serum was below 20.000 IU\ml (n=35). These patients comprised two comparison groups, in the control group the blood of healthy donors was studied, n=50. The study revealed that patients with a higher viral load such as clinical syndromes asthenovegetative and hepatomegaly, and changes in biochemical parameters (increased levels of total bilirubin, Alt, AST, GGT) were significantly more common (p<0.001) compared to both the comparison group and the control group. Cytokine status indicators (IL-2, INF-α, INF-γ) in initial examination of patients had significant differences depending on the initial level of viral load in the serum. When the amount of virus was over 20,000 IU\ml there was observed decrease in the concentration of cytokines, in HBV DNA below 20.000 IU\ml their level was close to reference values. The low level of cytokines IL-2, INF-α, INF-γ in patients with HBeAg-negative НBV and high viral load can be explained by the consequence of the negative impact on the immune system due to long-term persistence of immunological body reaction in HBV.
Aspirantskiy Vestnik Povolzhiya. 2016;16(5-6):26-29
26-29
MALT-LIMPHOMA OF THE STOMACH AND LYMPHOID HYPERPLASIA IN THE BACKGROUND OF HELICOBACTER-ASSOCIATED GASTRITIS: MORPHOLOGICAL AND IMMUNOHISTOCHEMICAL FEATURES
Abstract
The aim of the study was to identify new mechanisms of MALT-lymphoma of the stomach in patients with chronic H. pylori-associated gastritis. The article shows that the lowest level of the expression of Ki-67 and the molecule Bcl-2 is observed in lymphoid follicles of gastric mucosa in patients with chronic non-atrophic H. pylori-associated gastritis. Expression of Ki-67 and Bcl-2 has consistently increased in patients with chronic atrophic H. pylori-associated gastritis, reaching maximum values in patients with MALT-lymphoma of the stomach, which allows us to consider this as an option in the tumor progression of H. pylori-associated gastritis. The data obtained are able to improve the forecasting of H. pylori-associated gastritis.
Aspirantskiy Vestnik Povolzhiya. 2016;16(5-6):30-36
30-36
CRITERIA OF EFFICIENCY OF ANTIBACTERIAL THERAPY IN SEVERE CHRONIC OBSTRUCTIVE PULMONARY DISEASE
Abstract
The article is devoted to analysis of the impact of antimicrobial therapy in severe exacerbation of chronic obstructive pulmonary disease on the depth of remission. The dynamics of such indicators as spirographic indices and oxygen saturation in clinical observation groups with a random choice of the antibacterial drug and the formalization of the antibiotics list on the background of microbiological control were studied. The article demonstrates positive statistically significant changes of spirogram and pulse oximetry in the experimental group. The conclusion about the importance of optimized antibiotic therapy as a factor of the depth and quality of remission in severe chronic obstructive pulmonary disease is drawn. The dynamics of the main integrated indicators of lung function is presented.
Aspirantskiy Vestnik Povolzhiya. 2016;16(5-6):37-42
37-42
SUPPLEMENTARY METHODS IN DIET THERAPY OF OBESITY. LITERATURE REVIEW
Abstract
Searching for ways to support the treatment of obesity and to increase the effectiveness of diet therapy and lifestyle modifications are actively carried out nowadays. According to the latest scientific trends successful weight control is influenced by the correct combination of different food components, their timely elimination or supplementation, optimization of external influences, such as sleep quality as well as the psychological factors in the process of reducing excess body weight depending on the disease, age and the method of care. All of this contributes to following of dietary recommendations by obese patients.
Aspirantskiy Vestnik Povolzhiya. 2016;16(5-6):43-49
43-49
THE ABILITY TO PREVENT SEVERE PRE-ECLAMPSIA DUE TO INDIVIDUAL PREGRAVID PREPARATION
Abstract
Goal. The aim of the article is to assess the effectiveness of individual pregravid preparation with patients at risk of severe pre-eclampsia. Methods. The authors used the method of retrospective identification of risk factors for severe pre-eclampsia in 118 patients (study group) who did not receive pregravid preparation and delivery of up to 33 weeks, inclusive. Prospective evaluation of the effectiveness of individual pregravid preparation in the comparison group, formed by accident - control of 90 patients planning pregnancy was used. Results: In the first phase of the study comparative evaluation of medical histories and clinical characteristics of 118 patients in the main group and 100 pregnant women in the control group revealed the following risk factors of severe preeclampsia: pre-eclampsia in past medical history, chronic pyelonephritis, chronic hypertension, a combination of polymorphisms of hemostasis and folate cycle; obesity; essential hypertension in family history; age over 31 years. The average number of risk factors per one patient in the control group is 2,64±0,9 and 2,78±0,3. The course of pregnancy and its outcomes in patients with the individual pregravid preparation were significantly more favorable than in those without one: preeclampsia manifested only in 60% of cases and was moderate; delivery date was delayed (31,2 ± 1,7 and 37,2 ± 0,8, p <0.001), the frequency of operative delivery was less (100% and 30%, p <0.001), perinatal mortality (3.4% ) and severe lesions of the CNS in neonates (24.6%) occurred only in the main group. Conclusion: Individual pregravid preparation of high risk patients for severe pre-eclampsia an prevent its development in 40% of cases, reduce the severity of its symptoms in 60% of cases, prevent perinatal moertality and severe damage to the central nervous system of newborns with a decrease in frequency of operative deliveries in three times.
Aspirantskiy Vestnik Povolzhiya. 2016;16(5-6):50-54
50-54
IMPACT OF OBESITY ON FEMALE REPRODUCTIVE FUNCTION
Abstract
Standard body mass index or BMI categories fail to demonstrste corelatetion between obesity and the risk of poor reproductive function in young women. This article focuses on more specific risk factors associated with reproductive health in women apart increased BMI. The aim of this study was to evaluate the investigation of vaginal flora effectiveness as an existing screening routine technique on predicting poor reproductive outcome in obese women. For this reason we examined vaginal flora in 32 obese non-pregnant and 36 obese pregnant women. Also biochemical blood tests and examination of hormone levels was performed and compared with data obtained from 96 non-pregnant females with normal body mass index and without endocrine disorders. Unlike females with normal BMI obese patients were found to have dyslipidemia, increased level of inflammative proteins and leucocytes, activation of production of gonadotropin stimulating hormones and TSH with decreased level of prolactine, progesterone and free T4. In addition we found direct correlation between FSH, LH levels and BMI. The risk of vaginal dysbioses is not increased in obese women before and during pregnancy. Therefore further investigation and data are required in order to figure out valid route screening method in order to predict reproductive health risks in obese patients.
Aspirantskiy Vestnik Povolzhiya. 2016;16(5-6):55-61
55-61
STUDY OF INFLUENCE OF MEDICAL AND SOCIAL FACTORS ON THE EFFECTIVENESS OF IN VITRO FERTILIZATION IN SAMARA REGION
Abstract
Infertility caused by various disorders, is the only cause of the treatment of women in fertilization clinics. We performed a retrospective analysis of medical records of women who sought IVF in 2009 - 2014 in the Samara Center of Family Planning and Reproduction. 170 patients had IVF in their medical histories and 80 women with normal fertility and deliveries. It was found that such medical and social factors as age, professional experience, menstrual pattern, as well as gynecological and extragenital diseases in history have a statistically significant impact on the effectiveness of IVF.
Aspirantskiy Vestnik Povolzhiya. 2016;16(5-6):62-67
62-67
MODERN ASSAYS OF HEMOSTATIC SYSTEM IN OBSTETRIC PRACTICE
Abstract
The review presents the current assays of hemostatic system as well as methods of its research in obstetrics. The basic principles and steps of the coagulation tests are presented. They include from both screening at an early stage and clarification tests for a more detailed and in-depth examination. The article describes the advantages and disadvantages of the main methods of research which are actively used in everyday practice. Special attention is paid to the so-called “global” tests which assess the status of hemostatisis such as thromboelastography (TEG), trombodinamiks (TD), the thrombin generation test (TGT), a low-frequency pezoelektrometrii combined with thromboelastography (TEG). Interest to these tests has increased recently due to the existence of the imbalance between the understanding of the physiology of coagulation and the results of standard coagulation tests.
Aspirantskiy Vestnik Povolzhiya. 2016;16(5-6):68-73
68-73
CLINICAL EVALUATION OF PHYSIOLOGICAL AND PATHOLOGICAL LACTOGENESIS
Abstract
To accomplish the objectives of the study to evaluate the diagnostic value of the clinical method in relation to the pathological course of lactogenesis 180 women in childbirth were studied. 140 women suffered placental insufficiency of varying severity during pregnancy, 40 had physiological course of gestation. Subjective and objective clinical criteria of early hypogalactia were investigated in dynamics of lactogenesis on the third and the sixth day. Verification of the diagnosis of early hypogalactia was carried out by assessing the daily amount of milk and its conformity with the needs of a newborn. The results of the study have confirmed the negative impact of the functional placenta state disorder during pregnancy on the development of lactational function. The method of evaluation of objective and subjective clinical signs of pathological lactogenesis course showed low informativeness (Se = 57,1%, Sp = 61,7%, P = 46,5%). It was concluded that the clinical method has prognostic and diagnostic value in conjunction with more informative methods.
Aspirantskiy Vestnik Povolzhiya. 2016;16(5-6):74-78
74-78
THE CLINICAL REALIZATION OF FETAL PATHOLOGY ASSOCIATED WITH PLACENTAL INSUFFICIENCY
Abstract
The clinical realization of fetal pathology during gestation in pregnant in high risk group of decompensation of chronic placental insufficiency has been studied. The study revealed burdened obstetrical histories, somatic diseases, complicated gestation course and postpartum period, which justifies the necessity to use the prognostic scale of the risk factors for decompensation of placental insufficiency. This helps to select women of high risk for structural and functional abnormalities in placental system and perinatal pathology. It was revealed that a high morbidity and incidence of impaired early neonatal is due to the disruption in the functioning of the system «mother-placenta-fetus». This is the leading pathogenetic mechanism of impaired fetal condition. High frequency of the combination of growth retardation and fetal hypoxia proves pathogenetic unity of the two states associated with chronic placental insufficiency
Aspirantskiy Vestnik Povolzhiya. 2016;16(5-6):79-83
79-83
DIAGNOSIS OF PROLIFERATIVE DIABETIC RETINOPATHY USE OF FLUORESCE IN ANGIOGRAPHY IN
Abstract
Proliferative diabetic retinopathy (PDR) is one of the most common reasons of blindness among working age people. The use of modern methods of primary VE is accompanied by a low surgical risk and causes an improvement of visual and anatomical results. The main diagnostic procedures used in the PRD are direct ophthalmoscopy, fluorescein angiography (FAG) and optical coherence tomography (OCT). In the PDR their implementation is difficult because of violation of the vitreous transparency. Intraoperative FAG allows you to diagnose macular edema and ischemia, to determine the location of the retinal avascular regions and areas of neovascularization. The result is a more precise holding of the ELKS and therefore improve treatment outcome and reduction in the number of complications.
Aspirantskiy Vestnik Povolzhiya. 2016;16(5-6):84-87
84-87
PLATELET-RICH PLASMA IN MACULAR HOLE SURGERY. LITERATURE REVIEW
Abstract
The article provides review of the national and foreign literature on impotant aspects of the use of platelet-rich plasma in the surgicalt reatment of macular oles. In the last decade we have seen significant interest in this surgical technique, due to its efficiency with a high level of safety and low cost. Currently, platelet-rich plasma is actively used in various fields of medicine and has a number of useful properties. It accelerates the tissue regeneration, has anti-inflammatory and immunomodulatory effects. This gives great opportunites for its further application in ophthalmology.
Aspirantskiy Vestnik Povolzhiya. 2016;16(5-6):88-93
88-93
THE PROBABILITY OF OCCURRENCE OF POSTURAL DISORDERS AND THEIR FEATURES IN THE ELDERLY
Abstract
Postural disorders, an impaired ability to maintain balance while changing body position or walking, in elderly and senile patients are very frequent. They often fall and this results in the high rate of trauma in this age group. The aim of the study was to study the possible development of postural disorders in elderly patients as well as their objective assessment by using computer stabilometrics. This technique can also serve as a monitoring of the effectiveness of postural disorders therapy. Materials and methods. The change the postural function was studied in 47 patients (42 female and 5 male) whose age ranged from 60 to 74 years. Conclusion. The computer stabilometrics method allows to determine the likelihood of postural disorders development in elderly people and to assess their condition in dynamics.
Aspirantskiy Vestnik Povolzhiya. 2016;16(5-6):94-98
94-98
SECONDARY PREVENTION OF ACUTE ISCHEMIC STROKE BY MEANS OF CAROTID ENDARTERECTOMY
Abstract
The article discusses the results of the comparative analysis of 2 groups. The study group consists of 20 people and a comparison group of 14 patients. All patients suffered ischemic stroke and were treated Samara State Clinical Hospital №1 n.a. N.I. Pirogov. All patients of the study group demonstrated the occlusion or carotid stenosis greater than 60%, and these patients were performed CEA in the acuity. Patients in the control group having hemodynamically insignificant stenoses were not operated. Many patients demonstrated depression, anxiety disorder, almost all had cognitive impairments. One year follow-up revealed that most patients didn’t change their neurological status. Some of the patients having regression of neurological symptoms, the results in the study group were better. All patients noted improvement of health and general condition, reduction of depression and anxiety. Recovery of cognitive function was greater in the study group.
Aspirantskiy Vestnik Povolzhiya. 2016;16(5-6):99-102
99-102
THE EFFECTIVENESS OF THE OPERATION OF THE CORONAL DISPLACEMENT WITH PLASTIC DURA MATER “LIOPLAST»® IN ELIMINATION OF MULTIPLE GINGIVAL RECESSIONS
Abstract
The present study analyzed the results of surgical treatment of 11 patients in order to eliminate multiple gingival recessions Class I and Class II according to Miller. This intervention was carried by means of the bilaminar method, in which the mucous-periosteal flap was rotated and shifted coronally. Allogenic plastic material - dura “Lioplast» ® (DM) with a complete overlap of its muco-periosteal flap was placed and fixed beneath it. 68 gingival recessions were operated on. All patients were followed up within a year after surgery. Quantitative evaluation of the results was carried out taking into consideration a number of parameters in 6 and in 12 months after surgery. Complete root coverage in gingival recessions were observed in 97 % of cases in a one-year period after surgery, and the twofold increase of thickness of keratinized gingiva was also observed.
Aspirantskiy Vestnik Povolzhiya. 2016;16(5-6):103-106
103-106
CHANGE IN OPTICAL DENSITY OF A BONE IN CHRONIC GENERALIZED PARODONTITIS ASSOCIATED WITH THE REHABILITATION PROGRAM
Abstract
The article is devoted to modern concepts of medical rehabilitation of patients with parodontal disease. The results of a comprehensive examination, diagnosis and treatment of 95 patients suffering from chronic generalized parodontitis of moderate severity due to bruxism, the results of their research and conclusions are presented on the article.
Aspirantskiy Vestnik Povolzhiya. 2016;16(5-6):107-110
107-110
DOPPLEROGRAPHY OF THE PARODONTAL VESSELS ASSOCIATED WITH THE REHABILITATION OF PATIENTS WITH CHRONIC GENERALIZED PARODONTITIS
Abstract
The article is devoted to modern concepts of the relationship of parodontal disease and temporomandibular joint disease. The results of a comprehensive examination, diagnosis and treatment in 73 patients suffering from chronic generalized parodontitis of moderate severity due to bruxism, the results of their research and conclusions are presented in the article. Characteristic clinical features of these patients are demonstrated.
Aspirantskiy Vestnik Povolzhiya. 2016;16(5-6):111-117
111-117
LIFE QUALITY OF PATIENTS WITH TYPE 2 DIABETES NEEDING PROSTHODONTIC TREATMENT
Abstract
The study of life quality indicators of patients’ with type 2 diabetes and violation of dentition integrity has been done using МОS SF-36 and OHIP-14-RU questionnaires. Diabetic patients have more vivid changes of physical and psycho - emotional state with tooth loss than healthy people. The analyzed indicators justify the importance of their control in prosthodontic rehabilitation of patients with type 2 diabetes. The conclusions have been made about the necessity of studying life quality criteria in order to monitor the quality of serving dental patients.
Aspirantskiy Vestnik Povolzhiya. 2016;16(5-6):118-122
118-122
EXPERIENCE OF SURGICAL TREATMENT OF PATIENTS WITH BROAD FOREFOOT
Abstract
The aim of the article is the improvement treatment outcomes of patients with broad forefoot by applying a new method surgical intervention. The article investigates the results of surgical treatment of 47 patients with broad forefoot caused by fan-shaped divergence of the metatarsal bones. Correction of transverse arch is used as a new way of surgical treatment. Evaluation of treatment results was performed by using algofunctional scale, the measurement of the angles of the foot on radiographs and functional methods of examination of patients in the pre- and postoperative period (12 months after surgery). This is done with the accordance to the principles of evidence-based medicine. Good and satisfactory clinical results were achieved in 43 patients (91.5 %), treatment resulted in pain relieving, the loss of lameness ,the full restoration of the limb support function. This given example describes the results of the treatment with the use of the new method.
Aspirantskiy Vestnik Povolzhiya. 2016;16(5-6):123-126
123-126
HERNIA PATHOGENESIS IN PATIENTS WITH OBESITY. LITERATURE REVIEW
Abstract
The historical review of scientific literature devoted to the pathogenesis of hernias of different localizations in patients with obesity is presented in the article. Different views of scientists on their origin are described, an attempt of their systematization from the point of view of measures for disease prevention is made.
Aspirantskiy Vestnik Povolzhiya. 2016;16(5-6):127-130
127-130
FEATURES OF INFECTION CAUSATIVE AGENTS IN SURGICAL INTERVENTION SITE IN PATIENTS WITH INFECTED PANCREATIC NECROSIS
Abstract
The article analyzes the etiology of surgical site infection in 53 patients who underwent surgery for an infected pancreatic necrosis. The initiating agent of infection in the majority of cases were autochthonous bacteria Enterobacteriaceae. On the 5th day of the intensive care treatment 90% of patients became contaminated by hospital strains which contributed to the progression of the inflammatory process in the field of post-operative wounds in some patients. Appropriate antibiotic therapy and drainage of the flushing flow reduce the incidence of suppurative complications of wound healing caused by nosocomial infection.
Aspirantskiy Vestnik Povolzhiya. 2016;16(5-6):131-135
131-135
THE SUMMARY OF BLADDER CANCER RATE DYNAMICS IN SAMARA REGION
Abstract
Analysis of the dynamics of bladder cancer incidence in Samara region in 2005 - 2014 taking account of intensive and adjusted incidence rates shaowed stabilization of the rate averaged 13,40/0000 in 2005 and 11,40/0000 in 2007. The data are 23,30/0000 in 2005 and 19,50/0000 in 2014 in men, 5,5 и 4,5 respectively in women. Men get bladder cancer 4,6 times more than women. Maximum incidence both in men and women occurs at the age of 70 and older (130,80/0000and 16,30/0000 respectively). Although the incidence is stable in all age groups among men and women, the rates are still high. Consequently, it is necessary to examine Samara citizens regularly and refer to treatment as early as possible. Men and women aged 70 and older require specific attention for early disease detection.
Aspirantskiy Vestnik Povolzhiya. 2016;16(5-6):136-140
136-140
141-143
BENIGN BONE TUMORS. LITERATURE REVIEW
Abstract
The review is dedicated to the classification, epidemiology, clinical picture, localization, diagnosis and treatment of the most common benign tumors of the skeleton. Benign tumors of the musculoskeletal system is the major field in clinical oncology. The urgency of the problem is caused, first of all, by a very young and, as a consequence, the most socially significant contingent of patients with this pathology. Age of more than 70% of patients with bone tumors and soft tissue averaged 30 years, 30% of them are children under 15 years. In oncological diseases bone cancer tumors account for 1-4%. Diagnosis and selection of the optimal treatment strategy of these neoplasms become possible only due to multidisciplinary approach.
Aspirantskiy Vestnik Povolzhiya. 2016;16(5-6):144-149
144-149
RESULTS OF SUBTOTAL RESECTION OF THE SMALL INTESTINE IN ACUTE MESENTERIC CIRCULATION VIOLATION
Abstract
The study included 44 patients with acute mesenteric circulation, who underwent extensive resection of the small intestine associated with diffuse purulent peritonitis. Resection resulted in the formation transient end eyunostomy or Maydl’s eyunostomy. The factors that have a statistically significant effect on mortality in this group of patients (the integral scales MIP and SAPS). It was found that the length of the remaining part of the small intestine can not be a deterrent to the formation of the time limit eyunostomy. Based on these results the surgical algorithm was successfully applied in 28 patients of the main group, which reduced the mortality rate from 86.4% to 68%.
Aspirantskiy Vestnik Povolzhiya. 2016;16(5-6):150-154
150-154
CAUSES OF SYNDROME OF ACUTE STOMACH INJURY. LITERATURE REVIEW
Abstract
The article presents the literature review on risk factors of the development of acute erosive and ulcerative injuries of the upper gastrointestinal tract (GIT). This review discusses the etiology, epidemiology, and pathogenetic mechanisms of acute injuries development of the gastrointestinal mucosa and their prevention. Special attention is paid to the issues of erosive-ulcerative lesions in patients with sepsis, atherosclerosis, associated with the nonsteroidal anti-inflammatory drugs (NSAIDs) administration, and chronic diseases
Aspirantskiy Vestnik Povolzhiya. 2016;16(5-6):155-161
155-161
THE USE OF PLATELET-RICH AUTOPLASMA IN THE TREATMENT OF PATIENTS WITH PYOINFLAMMATORY DISEASES OF SOFT TISSUES, BONES AND JOINTS
Abstract
The advances of modern medicine are largely determined by the development and introduction of new technologies, which change the traditional understanding of treatment options. One of the most promising areas of scientific research, of course, is cell technologies. As for pyoinflammatory diseases of soft tissues, bones and joints it’s necessary to search for ways of stimulating angio - and osteogenesis in conditions of severe degradation of extracellular matrix and cell pool does not provide a favorable microenvironment for injected active cells. Hence, we can observe different performance of the methods based on the introduction of allo- or autologous cells and tissues from different patients associated with chronic inflammation. The solution seems to involve the drugs and methods which prepare the connective tissue due to remodulation of its structure, increase of hydrophilism, saturation of the growth factors necessary for the successful functioning of the cells. Such influence is sometimes ample for the achievement of the expressed clinical effect. The group of multimodal methods can reasonably be attributed to the treatment with platelet-rich plasma (PRP, PRP). Having been confirmed by numerous experimental and clinical studies, the biological effects of PRP can be considered such therapy as one of the most promising and not completely studied treatments.
Aspirantskiy Vestnik Povolzhiya. 2016;16(5-6):162-167
162-167
THE FIRST EXPERIENCE OF USING 320-SLICE CT PERFUSION IMAGING IN PROSTATE CANCER
Abstract
Introduction: Visualization of prostate cancer remains an actual problem in the urology and oncology. Purpose of the study: Evaluation of prostate cancer visualization using 320-slice perfusion computed tomography (PCT). Materials and methods: PCT results of 15 patients with suspected prostate cancer were evaluated. Studies were performed with the 320-slice spiral computed tomography Aquilion One (Toshiba, Japan). Perfusion of the prostate was calculated by the maximum gradient. Next to each perfusion map placed the zone of interest. For each area of interest the following indicators were taken into consideration: the average velocity of blood flow, normalized blood flow velocity, the difference of blood flow velocity in the contralateral areas of interest, the difference of the normalized blood flow velocity in the contralateral areas of interest. Differences between indicies and the results of histological examination for each zone of interest were evaluated by the variance analysis and by pairwise comparison with the Tukey’s criterion. Statistical significance of differences was assessed by the specialized computer language R v 3.2, using pROC packets. Results and conclusions: 180 biopsies were obtained. 19 ( prostate cancer Σ Gleason 6), 17 (prostate cancer Σ Gleason 7), 5 - (prostate cancer Gleason Σ 8), 7 (inflammation), 121 (no pathological), 11 (prostatic intraepithelial neoplasia (PIN)). The areas under the ROC curves for the studied parameters were: average blood flow rate 0.6343, normalized blood flow rate 0.5300, blood flow velocity difference in contralateral areas of interest 0.5875, normalized blood flow velocity difference in the contralateral areas of interest 0.6263. The obtained findings show a low sensitivity of the method in the detection of low-grade prostate cancer.
Aspirantskiy Vestnik Povolzhiya. 2016;16(5-6):168-174
168-174
EXPERIMENTAL INVESTIGATION OF STABLE FIXATION OSTHEOSYNTHESIS ASSOCIATED WITH OSTHEOPOROSIS BY MEANS OF NEW METAL RESTRAINT SYSTEM
Abstract
The article discusses the question of primary stability of osteoporotic bone fragments in osteosynthesis. New metal restraint system to solve the problem is suggested. Application of new metal restraint system in osteosynthesis of the medial malleolus associated with osteoporosis was tested on 16 bio models.
Aspirantskiy Vestnik Povolzhiya. 2016;16(5-6):175-178
175-178
AGE FEATURES AS A BASIS FOR FORMING OF RESERVES OF MEDICAL GOODS WHICH ARE USED FOR THE DELIVERY OF MEDICAL CARE TO PEDIATRIC PATIENTS IN EMERGENCY SITUATIONS
Abstract
In this article anatomical and physiological children’s features which are important for forming of reserves of medicines and other medical goods which are used for the delivery of medical care to pediatric patients in emergency situations have been analyzed. The necessity of inclusion in structure of these reserves of injectable medicines with small volumes has been founded. The importance of presence in structure of these reserves of medical goods with different sizes has been proved, it will allow to provide medical care to injured children of all ages.
Aspirantskiy Vestnik Povolzhiya. 2016;16(5-6):179-182
179-182
COMPARATIVE ANALYSIS OF ANATOMICAL AND HISTOLOGICAL FEATURES OF STEMS OF HEDYSARUM FRUTICOSUM PALL. AND HEDYSARUM ALPINUM L
Abstract
The article is devoted to a microscopic study of the stems of the Hedysarum fruticosum Pall. and Hedysarum alpinum L. to identify the anatomical and histological characteristics of previously unstudied species Hedysarum fruticosum. The analysis showed significant similarity of the stem structure of the two studied species genus Hedysarum. There is an intermediate type of the structure of the stele, the presence of marked hypodermis in H. fruticosum and H. alpinum. Bundles of young stems contain parenchyma cells with orange-brown pigment, wide lumens and a lot of mechanical fibers are found in the wood substance. However, specific features which can be used to determine the authenticity and quality of medicinal plant raw material were identified.
Aspirantskiy Vestnik Povolzhiya. 2016;16(5-6):183-187
183-187
ANALYSIS OF THE PUBLIC PROCUREMENT SYSTEM OF DRUGS OF THE CITY STERLITAMAK
Abstract
The article presents the results of the analysis of availiability of necessary medicines in Sterlitamak. The analysis average aggregate economic and social indicators in 2010 - 2015 is taken into consideration. It was established that the system of state social assistance meets the requirement of accessibility for the citizens of Sterlitamak.
Aspirantskiy Vestnik Povolzhiya. 2016;16(5-6):188-190
188-190
191-193
RESULTS OF THE STUDY OF COSMETOLOGISTPREFERENCES IN PERFUME AND BEAUTY PRODUCTS USED IN THE CENTERS AND BEAUTY SHOPS
Abstract
The article presents the results of research cosmetologist preferences. Cosmetologists are suppliers of cosmetic services by means of perfume and beauty products in cosmetology centers. The method of sociological poll - intramural and extramural questioning is used. The questionnaire is developed for the suppliers of cosmetic services. The following methods are chosen for assessment of preferences: Fishbeyn’s model; model with a parametrical index; complex approach; semantic differential. 56 cosmetologists including 19 dermatologists and 37 cosmetologists having dual education (major discipline - Cosmetology Nursing) took part in the assessment of the ProfiLIne products. The received results can be useful to experts in the field of pharmacy and when forming the product assortment of the small pharmaceutical enterprise.
Aspirantskiy Vestnik Povolzhiya. 2016;16(5-6):194-198
194-198
USE OF COMBINATORICS FOR FORENSIC ASSESSMENT OF EXTRAGENITAL INJURIES IN UNDERAGE FEMALE VICTIMS OF SEXUAL VIOLENCE
Abstract
The aim of the study is to evaluate the statistical indicators characterizing trauma-vulnerability of different parts of the body, in particular with the use of elements of combinatorics, in female child victims of sexual violence. As the object of study were archived data: experimental sample (n = 245) - the consequences of sexual violence; control sample (n = 275) - the results of not sexual violence. Statistically significant data showing the relationship damage combinations of different locations, or their absence, as appropriate external action.
Aspirantskiy Vestnik Povolzhiya. 2016;16(5-6):199-203
199-203
MYCOBACTERIOSIS: FEATURES OF EPIDEMIOLOGY AND LABORATORY DIAGNOSTICS
Abstract
The article is devoted to peculiarities of epidemiology and the modern methods of laboratory diagnosis of mycobacteriosis. The article presents the data on morbidity in developed countries during the period of the highest incidence of respiratory system mycobacteriosis. Risk factors of being infected with non-tuberculous mycobacteria which have an important clinical significance are also presented. The possibilities of identification of nontuberculous mycobacteria are given in the article.
Aspirantskiy Vestnik Povolzhiya. 2016;16(5-6):204-208
204-208
THE CONTENTS OF CYTOKINES TNF - Α AND IL-10 IN THE CONDITION OF SULFUR DIOXIDES IMPACT ON THE DIFFERENT STAGES OF ONTOGENY AND THE USE OF PROTECTOR
Abstract
The article studies cytokines: tumor necrosis factor (TNF) -Α and interleukin (IL) -10 in the peripheral blood of young rats, I and II levels of maturity and presenility under the influence of sulfur-containing gaseous pollutants. The shift to in the system «proinflammatory - anti-inflammatory» cytokines was revealed in the direction of the first factor, it is more pronounced in groups of young and presenile animals. The obtained results indicate the possibility of increasing the body's resistance to the toxic gas components due to the use of domestic «Etoksidol». Having anti-hypoxic and anti-oxidant action the drug helps to reveal the mechanisms and ways to increase non-specific protection in case of chronic exposure to hazardous environmental factors at different stages of postnatal ontogenesis.
Aspirantskiy Vestnik Povolzhiya. 2016;16(5-6):209-213
209-213
FOLLOWING PRINCIPLES OF RATIONAL NUTRITION IN THE ADULT POPULATION OF THE SAMARA REGION
Abstract
The article is devoted to studying of principles of rational nutrition the adult working population of the Samara region according to the evaluation of actual nutrition, a survey on healthy nutrition. The study identified the failure to comply with the principles of good nutrition on the grounds of qualitative and quantitative adequacy of the diet, imbalanced diet, eating disorders, disorders of cooking when cooking. These violations lead to the risk of development of alimentary-dependent diseases as well as reduce the adaptive capacity of the working population is employed in hazardous working conditions, as well as the population living under adverse environmental conditions.
Aspirantskiy Vestnik Povolzhiya. 2016;16(5-6):214-217
214-217
ANALYSIS OF WORK TIME EXPENDITURES OF A LOCAL PEDIATRICIAN IN AN OUTPATIENT SETTING
Abstract
The article describes fotohronometra measurements of a local pediatrician work hours. Work time expenditures for a single diagnostic and treatment visits, the annual load and the planned function of a local pediatrician are measured.Some suggestions for the optimization of the pediatric services are given.
Aspirantskiy Vestnik Povolzhiya. 2016;16(5-6):218-221
218-221
TO THE PROBLEM OF MOTIVATION OF MEDICAL HIGHT SCHOOLS GRADUATES TO FIND EMPLOYMENT IN MEDICAL INSTITUTIONS IN RURAL AREAS
Abstract
The article presents the results of a survey of medical high schools graduates, which reflect the professional motivation, socio-demographic characteristics of young professionals. The most significant social and labour incentives, according to young doctors that could promote the choice of medical institutions of rural areas were revealed. The article stresses the necessity to monitor the views of potential participants of programs of socio-economic incentives of young professionals of the rural health care system about the criteria determining the choice of the place of employment of the graduate.
Aspirantskiy Vestnik Povolzhiya. 2016;16(5-6):222-227
222-227