Pharmacy Formulas
A periodical scientific publication, the journal " Formulas of Pharmacy "(hereinafter-the publication), for publishing the main scientific results of dissertations for the degree of candidate of Sciences, for the degree of doctor of Sciences; presents high-quality, peer-reviewed research and interactive clinical content.
Our journal is focused on clinical pharmacologists, specialists of expert organizations, workers centers preclinical and clinical trials of medicinal products; employees of regulatory and Supervisory organizations and institutions in the field of pharmaceutical industry and Russian Ministry of health; researchers, medical and pharmaceutical workers of the organisations and institutions of the Ministry of health; experts of the scientific organizations of RAS and other researchers in the field of environmental security.
The topics of published materials are limited to two branches of science - medical and biological - and they correspond to groups of scientific specialties (03.02.00 General biology, 14.03.00 Biomedical sciences, 14.04.00 Pharmaceutical sciences) in accordance with the order of the Ministry of Education of the Russian Federation dated October 23, 2017 No. 1027 "On the approval of the nomenclature of scientific specialties for which science degrees are awarded" and by order of the Ministry of Education and Science of the Russian Federation of December 12, 2016 No. 1586 (revised March 27, 2018) "On the approval of the rules for forming the list of peer-reviewed scientific publications."
The publication complies with modern rules and requirements of domestic and foreign legislation for peer-reviewed scientific publications.
Journal strategy
When preparing each issue, members of the editorial Board intend to take into account modern requirements for the order of qualified review, information openness and bibliometric indicators in assessing the publication activity of authors, along with other factors of the journal.
To this end, the editorial team uses rigorous: editorial, expert, and statistical review processes to evaluate manuscripts for scientific accuracy, novelty, and importance; policies and practices that ensure that authors disclose all relevant financial associations and that such associations do not in any way affect the content published by the journal.
When developing the strategy and layout of the publication, we studied and analyzed the professional materials available to us from information resources of publishers and owners of bibliographic and abstract databases-leaders of international citation systems for relevant branches of science and groups of scientific specialties.
In the course of this work, three groups of scientific specialties were identified, which, in our opinion, made it possible to create a publication's rubricator and determine its name: "Pharmacy Formulas". At the same time, we took into account the definition of pharmacy as the entire life cycle of medicines, including the creation, preclinical and clinical research, production technology, organization of pharmaceutical business, as well as issues of control and analytical research, food and environmental safety. In turn, the word "formulas" means directions, trends, trends in the development of scientific and practical areas that make up pharmacy.
We believe that through our efforts, the journal will keep healthcare and pharmaceutical industry professionals at the forefront of medical and pharmaceutical knowledge, help them deepen their understanding of new areas of interest, and provide valuable insights into scientific and practical medical and pharmaceutical activities.
Authors and readers
To present the results of high-quality scientific research to the reader, we are ready to be responsible for preparing the manuscript to meet the requirements of the journal, quality review of manuscripts , preparing the article for publication, providing opportunities and scientific communications of the founders of the publication to promote the article.
The journal's website meets all the requirements of the international bibliographic database. Full electronic document flow for authors, reviewers, scientific and literary editors is carried out on our own platform.
To promote the article, authors will be able to use the personal website of the publication; assignment of the DOI identifier of the author's manuscript immediately after uploading to the site; unique author ID ORCID; professional social networks Google Scholar, ResearchGate; repositories; open electronic archives; bibliography management system; social media; registration of the scientist as a reviewer; assistance in preparing the use of media (materials for press releases, interviews).
The publishing house of the journal has direct channels for transmitting information to the RSCI and international databases: Scopus, Web of Science, PubMed, CNKI.
When developing all the tasks facing the members of the editorial Board and editorial Board of the journal "Formulas of Pharmacy", we share a common goal: to promote and actively participate in scientific communications on the declared groups of scientific specialties in the biomedical field and pharmacy, from the idea to the release of medicines to the consumer market and management of their waste and metabolites.
Media registration certificate: ПИ № ФС 77 – 76969 from 11.10.2019
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Current Issue
Vol 6, No 4 (2024)
- Year: 2024
- Articles: 6
- URL: https://journal-vniispk.ru/PharmForm/issue/view/18359
- DOI: https://doi.org/10.17816/phf_64
Full Issue
Pharmaceutical Sciences
Functional reserves and adaptive capabilities of the body in conditions of oxidative stress
Abstract
The review is devoted to the problem of forming functional reserves and increasing the adaptive capabilities of the human body to the action of negative factors of various nature, including those accompanied by violations of the antioxidant status. Functional reserves are determined by the metabolic and bioenergetic capabilities of the body, as well as the possibility of interaction of organs and body systems for self-regulation and optimization of its physiological functions. The levels of functional reserves determine the body’s ability to adapt urgently or long-term. Oxidative stress is a non–specific pathogenetic process that develops as a result of a sharp increase in oxidative (free radical, peroxide) processes with insufficient functioning of the endogenous antioxidant system of the body. Almost all pathological conditions are more or less accompanied by the development of oxidative stress, which determines the relevance and prospects of this study. Urgent and long-term compensatory mechanisms in oxidative stress are associated with the optimization of cellular energy supply and the state of the endogenous antioxidant system of the body, in which a special role belongs to the correction of mitochondrial disorders. Ensuring the functional capabilities of the body for urgent adaptation is possible using a complex of pharmacological preparations of multifunctional action based on antioxidants. Increasing the effectiveness of the formation of long-term adaptation is advisable due to the moderate and short-term effect of prooxidants on the body, for example, in widespread hypoxic training.
10-17
Biomedical Sciences
The state of oncological care in Russia: malignant skin neoplasms (C44). Part 1. Prevalence, quality of accounting, age characteristics, localization, and histological structure (clinical-population study)
Abstract
This work represents a clinical-population study of the state of oncological care in Russia, focused on malignant skin neoplasms (C44). The study analyzes data on the prevalence of this disease, the quality of case accounting, age characteristics, and the localization and histological structure of tumors. The aim of this research is to continue the investigation into the patterns of prevalence of skin neoplasms (C44), assess the quality of primary accounting, and evaluate the impact of the coronavirus infection epidemic on analytical indicators of prevalence and patient survival. The conducted study confirmed the trend of increasing morbidity and decreasing mortality from skin neoplasms (C44) among the population of Russia and the Northwestern Federal District of the Russian Federation. A clear positive dynamics in the quality of accounting is observed. Special attention is given to the specifics of morbidity changes in neoplasms (C44) considering each age group of the population of Russia. At the population level, the age-specific mortality of patients is presented for each year of observation, analyzed in the context of five-year cohort groups. For the first time, a trend has been identified showing an increase in annual mortality from skin neoplasms (C44) after the sixth year of observation following the treatment of patients.
18-33
The state of cancer care in Russia: malignant tumors of the skin (C44). One- and five-years survival of patients, age characteristics. Part II
Abstract
Pancreas cancer (С25) is a cancer with an unfavorable prognosis, remains one of the most lethal types of cancer, at the national level mortality exceeds morbidity. The analysis of patient survival at the population level on the scale of federal districts is not carried out in Russia with the exception of the North-West Federal District. Considering that the levels of standardized rates of morbidity and mortality from pancreas cancer are close in Russia and NWFD, and the value of index of accuracy practically coincide, the results of the population cancer registry (PCR) of the NWFD RF actually characterize the state of cancer care on average in Russia, with the exception of autonomous districts. The aim of the second stage of the study was to identify the true state of the effectiveness of the oncological service in Russia by calculating a key parameter – evaluating its performance, specifically, calculating the leading parameter – the survival rate of patients, taking into account the stage, localization, histological structure, and the possibility of curing patients The conducted research made it possible to determine the effectiveness of providing specialized oncological care to patients with pancreas cancer at the federal district level. An increase in the one–year observed survival rate for the period from 2000 to 2004 to 2015-2019 was established from 16.0 to 21.8% or by 36.3%, and five–year from 5.1 to 6.0%. The median survival rate did not reach 4 years. A significant difference in the levels of one-year survival of patients in different age groups has been established. Significant defects in the distribution of patients according to the stage of the disease were revealed. The specification of patient survival by detailed localization groups and major histotypes of tumors was studied.
36-50
Actual problems: discussion tribune
Environmental and economic aspects of improving the energy efficiency of the vaccine production life cycle
Abstract
The work is devoted to the analysis of the impact of energy efficiency improvements on the environmental and economic aspects of the vaccine production life cycle. In the context of the growing need for global vaccination and taking into account significant losses due to violations of the cold chain, the study focuses on reducing energy consumption and optimizing resource use. The analysis of costs, greenhouse gas emissions, and the impact on the cost of vaccines will determine the economic and environmental benefits of implementing energy-efficient technologies, contributing to sustainable development and increasing the availability of vaccination.
52-57
Biological sciences
The eukaryotic system in the third update of the interface “Eukaryotic supergroups: Taxonomy/Biotechnology interface”: Formal procedures for rank changes
Abstract
The problem of coordinating the ranks of higher eukaryotic taxa was specifically considered by us in the monograph and a recent article. However, we omitted most of the formal descriptions of the proposed taxa in the new rank. The purpose of this article is a formal description of a number of taxa established by us in the monograph “Nomenclature and rank correlation of higher taxa of eukaryotes and subsequent interface updates”. Here we formally described such taxa as Eocorticata regn. nov., Tsaralia regn. nov., Apusomonadea intraregn. nov., Breviatea intraregn. nov., Eochromista superphyl. nov., Zoosporia superphyl. nov., Eurhodophyta div. nov., Proteorhodophyta div. nov., Anaeramoebea phyl. et cl. nov., Calkinsea phyl. nov., Meteora phyl. nov., Syssomonadea phyl. nov., Chlorodendrophytina subdiv. nov., Chloropicophytina subdiv. nov., Dikaryomycotina subdiv. nov., Pedinophytina subdiv. nov., Picocystophytina subdiv. nov., Sanchytriomycotina subdiv. nov., Agaricomycia supercl. nov., Calcarisporiellomycia supercl. nov., Ceratiomyxomycia supercl. nov., Chytridiomycia supercl. nov., Entomophthoromycia supercl. nov., Entorrhizomycia supercl. nov., Kickxellomycia supercl. nov., Mortierellomycia supercl. nov., Mucoromycia supercl. nov., Myxogasteromycia supercl. nov., Monoblepharomycia supercl. nov., Neocallimastigomycia supercl. nov., Saccharomycia supercl. nov., Acytosteliomycetes cl. nov., Liceomycetes cl. nov., Microheliellida cl. nov., Paratrimastigidea cl. nov., Protosporangiomycetes cl. nov., Pycnococcophyceae cl. nov. The main trends of further improvement of the rank structure of the eukaryote tree we see in 1) some multiplication of the supregroups described for the few taxa now located among the Amoebozoans and TSAR, as well as many environmental sequences; 2) further rationalization of the Fungi and Metazoa system using intercalary taxonomic categories (including additional and not prescribed in both nomenclatural codes ones), and 3) further automatization of the ranking procedure and solving the problem of rank estimating for distant “orphan” taxa.
58-75
Heritage
Significant contribution of scientist David Zilber to the development of domestic hygiene and pharmaceutical education
Abstract
The essay is dedicated to Professor David Abelievich (or Aleksandrovich) Zilber, who made significant contributions to the development of educational activities at the Leningrad Chemical-Pharmaceutical Institute. The foundation of this research is based on available archival materials, including family documents, which allowed for a deeper understanding of his multifaceted professional activity. The analysis of documentary sources and published works of D. A. Zilber reveals not only his organizational efforts but also his innovative scientific approaches in the field of occupational hygiene. His role in training specialists — engineers, chemists, and technologists — capable of successfully working in the chemical-pharmaceutical industry is hard to overestimate. The essay presents a brief historical and biographical study that recreates the image of a prominent scientist and a brilliant organizer of science. It briefly describes the scientist’s activities at the 2nd Leningrad Medical Institute and the Leningrad Institute of Occupational Hygiene and Professional Diseases. It highlights not only David Zilber’s professional achievements but also his personal qualities, such as determination, persistence, and dedication, which contributed to his success. Zilber’s works and ideas continue to influence modern approaches to the hygienic education of pharmaceutical workers.
81-92